AOD-9604 (Anti-Obesity Drug 9604) is a synthetic fragment of human growth hormone, specifically the C-terminal fragment (hGH 177-191). It was originally developed by Metabolic Pharmaceuticals as a weight loss drug. Unlike full HGH, AOD-9604 targets fat metabolism specifically — it stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat storage) without affecting blood sugar or IGF-1 levels.
How long does AOD-9604 take to work?
▼
AOD-9604 effects on fat metabolism begin within a few hours of injection, but visible body composition changes typically take 8–12 weeks of consistent daily dosing. Most users report noticeable results in stubborn fat areas (abdomen, love handles) within 2–3 months. It is often combined with other peptides — particularly BPC-157 and ipamorelin — for a comprehensive weight loss and recovery stack.
Is AOD-9604 the same as HGH fragment 176-191?
▼
AOD-9604 is sometimes used interchangeably with 'HGH fragment 176-191' but they differ slightly: fragment 176-191 spans amino acids 176–191, while AOD-9604 spans 177–191. The practical effects are nearly identical. Both isolate the fat-burning portion of HGH while eliminating the growth-promoting and insulin-desensitizing effects of full HGH. 'HGH frag' and AOD-9604 are used by the same population for the same purpose.
